In fact, I believe that hCG is a necessary component of TRT and should be used in most men who consider using testosterone. Primary Testicular Failure. Dosage protocols vary, but since it stays in the system for about 3 days most doctors prescribe 250-500 units 1-2x/week. When you inject the HCG, the enzyme is stimulated again and the pathway flows normally. Oestrogens and spermatogenesis. Nedresky D, Singh G. Physiology, Luteinizing Hormone. Wipe skin with alcohol swab at intended injection site and let dry. It is not uncommon for women to require a dose as high as 200 iu. .5 twice a week Never used HCG. Taking HCG can keep this from happening. hCG plays an important and critical role in men who are undergoing TRT (testosterone replacement therapy). J Clin Endocrinol Metab. 2018 Jul;7(Suppl 3):S348-S352. Injections of hCG are also sometimes used as an alternative to testosterone products in men with testosterone deficiency. Fertil Steril. Using one of the insulin syringes, hold the HCG vial upside down and draw up either 0.25mL or 0.5mL depending on your prescription. Always consult with your health practitioner before beginning any treatment program, especially if pregnant or nursing. PMID: 29772111. HCG can also help maintain fertility during TRT. Unfortunately it is not a dose dependent relationship and as the length of the penis is restricted by the suspensory ligament, you cant defy genetics! For myself, only on Test at 125mg/week unless I decide to add in something like HCG by myself. It’s often the difference between feeling good and feeling great. I always recommend the use of HCG to all new patients, irrespective of the need to retain fertility, for the reasons discussed above. In: Simoni M., Huhtaniemi I. For long-term therapy, a higher dose of 4,000IU administered 3 … All Rights Reserved, Available from: https://www.ncbi.nlm.nih.gov/books/NBK539692/, Available from: https://www.ncbi.nlm.nih.gov/books/NBK279076/, Available from: https://www.ncbi.nlm.nih.gov/books/NBK482481, The Men’s Health Clinic TRT Management Guidelines, Dispelling The Myths: TRT & Cardiovascular Health, Dispelling the Myths: Prostate Cancer & Testosterone Replacement Therapy (TRT), Microdosing TRT – The Future of Testosterone Replacement Therapy, Possible Up-regulation of Steroid Hormones, Janet Choi, Johan Smitz, Luteinizing hormone and human chorionic gonadotropin: Origins of difference, Molecular and Cellular Endocrinology, Volume 383, Issues 1–2, 2014, Pages 203-213, ISSN 0303-7207, https://doi.org/10.1016/j.mce.2013.12.009. Fatigue, impotence, water retention (bloat), depression, and brain fog are all commonly associated with high estrogen. There are also other considerations outside of the obvious benefit in maintaining testicular function. Transl Androl Urol. IMC remedies, nutritional products, and treatment modalities are intended to enhance overall health and are not intended or implied to diagnose, treat, prevent, or cure any specific illness. ITT is key for proper sperm production. The cash price is typically at least $250. Springer, Cham. This further suppresses the release of LH and Follicle Stimulating Hormone (FSH) from the pituitary gland. [Updated 2015 Aug 30]. 2015 Nov;76:57-62. doi: 10.1016/j.yhbeh.2015.06.020. During your 43 day protocol with HCG, mix only one vial … Continue reading HCG Injection Instructions and Dosage TRT – Best Practice explains my rationalisation. It’s a complicated mechanism that involves both gene expression and downstream steroid synthesis 2. doi: 10.21037/tau.2018.04.11. It is made by the placenta and helps maintain pregnancy. When taking testosterone replacement therapy (TRT) the pituitary stops sending these signals and over time the testes may shrink in size leading to a decrease in native testosterone production and a decline in fertility. The beta subunits of these hormones differ in amino acid sequence. HCG is self administered as an injection into the subcutaneous fat, similar to insulin, with a tiny needle. It is due to this action that testosterone monotherapy has been investigated as a potential male contraceptive 8. Based on the studies, there are a few approaches here. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. The medical dosing of Human Chorionic Gonadotropin has always been 5000 IU in injectable form. A 250 unit dose would equal 0.25mL, and a 500 unit dose would equal 0.5mL. An 8 Week Steroid Cycle With Trenbolone and Dianabol. We have found that the HCG is effective for closer to 60 days. I’ll often talk about estrogen more than testosterone when discussing TRT as it’s the single hardest hormone to control in men. I've used lower doses like 250 i.u. In order to appreciate the importance of HCG in TRT, you firstly need to understand the Hypo-Pituitary Gonadal (HPG) Axis and the role of LH within this axis and throughout the human body. Do you need HCG with TRT? We also discussed earlier how HCG mimics LH. Whether that be due to a disproportionate ratio of testosterone to oestradiol, or a negative effect on the Central Nervous System which manifests itself as anxiety, is unclear. This ITT decrease is due to the LH and FSH shut down that occurs with TRT. How to take HCG. Testosterone Replacement Therapy should be considered as Hormone Replacement Therapy. Despite the science and extremely positive outcomes we have had from using HCG alongside TRT, there are no certainties in medicine and so if you are concerned about fertility whilst on TRT, I would recommend having a semen sample frozen as a precautionary measure. The HCG molecule shares similarities with the LH molecule, however its structure is not chemically identical. BH22 9BU, Copyright ©2021 Preventative Health Doctors Limited trading as ‘The Men’s Health Clinic’ - Company No. Spermatogenesis is the process by which haploid spermatozoa are formed from germ cells. Please notify us if redness/bruising around the injection site appear to be enlarging or spreading. Opinion is currently divided amongst Endocrinologists regarding the benefit of HCG in TRT due to the traditional treatment model always having been testosterone monotherapy. Categorized in: Articles, Conditions, HCG, Hormone Replacement, Men's Health, © 2021 Copyright Integrative Medicine Center of Western Colorado. If you remove a part of the jigsaw, you will never see the complete picture. Whilst the study was conducted in men with a micro-penis, many of my patients report a fullness with HCG that they note decreases on cessation. Testosterone monotherapy is a rather short-sighted and dogmatic approach to treating Testosterone Deficiency (TD) when we know other hormones are suppressed through treatment. Just curious, why would you want to … https://themenshealthclinic.co.uk/the-benefits-of-using-hcg-with-trt Behre HM, Bergmann M, Simoni M, et al. 11) What dose do you run HCG at? Site by RSM. But if your weight loss goal is 15 pounds or less, you can do the 23 days protocol and you will need only one 5000 IU vial. [Updated 2020 Sep 30]. The Men's Health Clinic
But if your weight loss goal is 15 pounds or less, you can do the 23 days protocol and you will need only one 5000 IU vial. It is worth keeping in mind that the positive effects of HCG in maintaining testicular functions is very dependent on the viability of the testes at the time of diagnosis. Shares. Patel AS, Leong JY, Ramos L, Ramasamy R. Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility. For more information on HCG, please refer to our HCG Fact Sheet. There are workarounds to these issues; one such protocol is to simultaneously use human chorionic gonadotropin (HCG) - an analog of the LH that your pituitary gland produces - along with TRT. Remove cap off of needle and administer medication subcutaneously: The injection should be given in the subcutaneous fat anywhere around the abdomen, Pinch skin at injection site into a mound between thumb and forefinger and hold the syringe like a pencil with the other hand, Push the needle through skin at a 90-degree angle until needle disappears, Gently pull back on plunger until a small air bubble appears in the syringe (if blood appears in the syringe, do not panic, pull the needle out a bit, change direction, push back all the way in until needle disappears under skin), then inject medication, Pull needle out of skin and wipe injection site with an alcohol swab, rubbing the site gently (this will help the absorption of the medication); occasionally a small amount of blood will be visible, which is not a reason for any concern. If you're using HCG alone, according to the study above where it was directly compared to TRT… Average post-treatment FT levels were 14.7 pg/mL in the CC monotherapy portion of the study and 22.0 pg/mL in the adjuvant CC portion. How much Arimidex should I take on TRT? Remove the syringe and replace the cap until ready to give the injection. Taking your HCG shot 2 days before the test shot would do it. HCG mimics Lutenising Hormone (LH). Andrea D. Coviello, Alvin M. Matsumoto, William J. Bremner, Karen L. Herbst, John K. Amory, Bradley D. Anawalt, Paul R. Sutton, William W. Wright, Terry R. Brown, Xiaohua Yan, Barry R. Zirkin, Jonathan P. Jarow, Low-Dose Human Chorionic Gonadotropin Maintains Intratesticular Testosterone in Normal Men with Testosterone-Induced Gonadotropin Suppression.
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